Search for potential biomarkers of inveterate dermatoses by means of proteomic analysis



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Abstract

The review covers the key achievements of proteome studies using mass spectrometry and two-dimensional electrophoresis methods in the field of dermatology Works studying the most prevalent chronic dermatoses such as psoriasis, atopic dermatitis, acne vulgaris and mycosis fungoidea are examined. Proteome analysis in dermatology is a promising technique today because it makes it possible to study molecular pathogenic mechanisms of skin chronic diseases in a greater detail. In addition, proteome technologies are aimed at searching for potential disease biomarkers and targets for drugs.

References

  1. Gygi S. P., Aebersold R. Mass spectrometry and proteomics // Curr. Opin. Chem. Biol. 2000. Vol. 4. P. 489-494.
  2. Nesvizhskii A. I. Protein identification by tandem mass spectrometry and sequence database searching // Methods. Mol. Biol. 2007. Vol. 367. P. 87-119.
  3. Andreeva A. V., Kutuzov M. A., Voyno-Yasenetskaya T. A. A ubiquitous membrane fusion protein alpha SNAP: a potential therapeutic target for cancer, diabetes and neurological disorders? // Expert. Opin. Ther. Targets. 2006. Vol. 10. P. 723-733.
  4. Blumenberg M. Skinomics // J. Invest. Dermatol. 2005. Vol. 124. P. viii-x.
  5. Carlen L. M., Sanchez F., Bergman A. C., Becker S., Hirschberg D., Franzen B., Coffey J., Jornvall H., Auer G., Alaiya A. A., Stahle M. Proteome analysis of skin distinguishes acute guttate from chronic plaque psoriasis // J. Invest. Dermatol. 2005. Vol. 124. P. 63-69.
  6. Celis J. E., Cruger D., Kiil J., Lauridsen J. B., Ratz G., Basse B., Celis A. Identification of a group of proteins that are strongly up-regulated in total epidermal keratinocytes from psoriatic skin // FEBS Lett. 1990. Vol. 262. P. 159-164.
  7. Celis J. E., Madsen P., Rasmussen H. H., Leffers H., Honore B., Gesser B., Dejgaard K., Olsen E., Magnusson N., Kiil J., et al. A comprehensive two-dimensional gel protein database of noncultured unfractionated normal human epidermal keratinocytes: towards an integrated approach to the study of cell proliferation, differentiation and skin diseases // Electrophoresis. 1991. Vol. 12. P. 802-872.
  8. Collier C. N., Harper J. C., Cafardi J. A., Cantrell W. C., Wang W., Foster K. W., Elewski B. E. The prevalence of acne in adults 20 years and older // J. Am. Acad. Dermatol. 2008. Vol. 58. P. 56-59.
  9. Cowen E. W., Liu C. W., Steinberg S. M., Kang S., Vonderheid E. C., Kwak H. S., Booher S., Petricoin E. F., Liotta L. A., Whiteley G., Hwang S. T. Differentiation of tumour-stage mycosis fungoides, psoriasis vulgaris and normal controls in a pilot study using serum proteomic analysis // Br. J. Dermatol. 2007. Vol. 157. P. 946-953.
  10. Domae M., Sagara H., Sakaue M., Fukuda T., Kamikawa Y. The antiallergic drug oxatomide promotes human eosinophil apoptosis and suppresses IL-5-induced eosinophil survival // J. Allergy Clin. Immunol. 2003. Vol. 111. P. 567-572.
  11. Guldbakke K. K., Khachemoune A. Guttate psoriasis // Dermatol. Nurs. 2006. Vol. 18. P. 369.
  12. Hensbergen P., Alewijnse A., Kempenaar J., van der Schors R. C., Balog C. A., Deelder A., Beumer G., Ponec M., Tensen C. P. Proteomic profiling identifies an UV-induced activation of cofilin-1 and destrin in human epidermis // J. Invest. Dermatol. 2005. Vol. 124. P. 818-824.
  13. Huang C. M., Elmets C. A., van Kampen K. R., Desilva T. S., Barnes S., Kim H., Tang D. C. Prospective highlights of functional skin proteomics // Mass Spectrom. Rev. 2005. Vol. 24. P. 647-660.
  14. Huang C. M., X. H., Wang C. C., Elmets C. A. Proteomic characterization of skin and epidermis in response to environmental agents // Expert. Rev. Proteomics. 2005. Vol. 2. P. 809-820.
  15. Issaq H. J., Conrads T. P., Prieto D. A., Tirumalai R., Veenstra T. D. SELDI-TOF MS for diagnostic proteomics // Anal. Chem. 2003. Vol. 75. P. 148A-155A.
  16. Jugeau S., Tenaud I., Knol A. C., Jarrousse V., Quereux G., Khammari A., Dreno B. Induction of toll-like receptors by Propionibacterium acnes // Br. J. Dermatol. 2005. Vol. 153. P. 1105-1113.
  17. Kim W. K., Cho H. J., Ryu S. I., Hwang H. R., Kim D. H., Ryu H. Y., Chung J. W., Kim T. Y., Park B. C., Bae K. H., K. Y., Lee S. C. Comparative proteomic analysis of peripheral blood mononuclear cells from atopic dermatitis patients and healthy donors // BMB Rep. 2008. Vol. 41. P. 597-603.
  18. Krueger J. G., Bowcock A. Psoriasis pathophysiology: current concepts of pathogenesis // Ann. Rheum. Dis. 2005. Vol. 64 Suppl 2. P. ii30-36.
  19. Lottspeich F. Proteome Analysis: A Pathway to the Functional Analysis of Proteins // Angew Chem. Int. Ed. Engl. 1999. Vol. 38. P. 2476-2492.
  20. Madsen P., Rasmussen H. H., Leffers H., Honore B., Celis J. E. Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty acid-binding protein [PA-FABP]) that is highly up-regulated in psoriatic skin and that shares similarity to fatty acid-binding proteins // J. Invest. Dermatol. 1992. Vol. 99. P. 299-305.
  21. Nakatsuji T., Shi Y., Zhu W., Huang C. P., Chen Y. R., Lee D. Y., Smith J. W., Zouboulis C. C., Gallo R. L., Huang C. M. Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo // Proteomics. 2008. Vol. 8. P. 3406-3415.
  22. Nickoloff B. J., Nestle F. O. Recent insights into the immunopatho- genesis of psoriasis provide new therapeutic opportunities // J. Clin. Invest. 2004. Vol. 113. P. 1664-1675.
  23. Park J. H., Choi Y. L., Namkung J. H., Kim W. S., Lee J. H., Park H. J., Lee E. S., Yang J. M. Characteristics of extrinsic vs. intrinsic atopic dermatitis in infancy: correlations with laboratory variables // Br. J. Dermatol. 2006. Vol. 155. P. 778-783.
  24. Park Y. D., Kim S. Y., Jang H. S., Seo E. Y., Namkung J. H., Park H. S., Cho S. Y., Paik Y. K., Yang J. M. Towards a proteomic analysis of atopic dermatitis: a two-dimensional-polyacrylamide gel electrophoresis/mass spectrometric analysis of cultured patient-derived fibroblasts // Proteomics. 2004. Vol. 4. P. 3446-3455.
  25. Park Y. D., Lyou Y. J., Yang J. M. Detection of down-regulated acetaldehyde dehydrogenase 1 in atopic dermatitis patients by two-dimensional electrophoresis // Exp. Dermatol. 2007. Vol. 16. P. 130-134.
  26. Park Y. D., Lyou Y. J., Yang J. M. Two-dimensional electrophoresis analyses of atopic dermatitis and the chances to detect new candidate proteins by the variations in immobilized pH gradient strips // J. Dermatol. Sci. 2007. Vol. 47. P. 9-17.
  27. Pawin H., Chivot M., Beylot C., Faure M., Poli F., Revuz J., Dreno B. Living with acne. A study of adolescents' personal experiences // Dermatology. 2007. Vol. 215. P. 308-314.
  28. Plavina T., Hincapie M., Wakshull E., Subramanyam M., Hancock W. S. Increased plasma concentrations of cytoskeletal and Ca2+ - binding proteins and their peptides in psoriasis patients // Clin. Chem. 2008. Vol. 54. P. 1805-1814.
  29. Purdy S., de Berker D. Acne // Bmj. 2006. Vol. 333. P. 949-953.
  30. Rahman P., Elder J. T. Genetic epidemiology of psoriasis and psoriatic arthritis // Ann. Rheum. Dis. 2005. Vol. 64 Suppl 2. P. ii37-39; discussion ii40-31.
  31. Takeda A., Higuchi D., Takahashi T., Ogo M., Baciu P., Goetinck P. F., Hibino T. Overexpression of serpin squamous cell carcinoma antigens in psoriatic skin // J. Invest. Dermatol. 2002. Vol. 118. P. 147-154.
  32. Tom W. L., Barrio V. R. New insights into adolescent acne // Curr. Opin. Pediatr. 2008. Vol. 20. P. 436-440.
  33. Tsujimoto Y., Shimizu S. The voltage-dependent anion channel: an essential player in apoptosis // Biochimie. 2002. Vol. 84. P. 187-193.
  34. Yoon S. W., Kim T. Y., Sung M. H., Kim C. J., Poo H. Comparative proteomic analysis of peripheral blood eosinophils from healthy donors and atopic dermatitis patients with eosinophilia // Proteomics. 2005. Vol. 5. P. 1987-1995.
  35. Zackheim H. S., McCalmont T. H. Mycosis fungoides: the great imitator // J Am Acad Dermatol. 2002. Vol. 47. P. 914-918.
  36. Zouboulis C. C. Acne and sebaceous gland function // Clin. Dermatol. 2004. Vol. 22. P. 360-366.
  37. Говорун В. М., Арчаков А. И. Протеомные технологии в современной биомедицинской науке // Биохимия. 2002. Т. 67. 1341 - 1359.

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