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Studies on effectiveness and safety of system retinoids use in therapy ofadolescent acne
- Authors: Murashkin NN1, Ivanov AM1, Zaslavsky DV1, Kamilova TA1
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Affiliations:
- Issue: Vol 86, No 5 (2010)
- Pages: 112-116
- Section: Articles
- Submitted: 11.03.2020
- Published: 15.10.2010
- URL: https://vestnikdv.ru/jour/article/view/983
- DOI: https://doi.org/10.25208/vdv983
- ID: 983
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Abstract
The article describes up-to-date data on mechanics of epigenetic effects of system retinoid - isotretinoin (Roaccutane). It is
noted, that modern acne therapy is able not only to pathogenetically influence consequences of the process, but effect genetical
causes of desease, leading to persistant changes and normalization of regulatory segments DNA structure under influence of
isotretinoin. Also this article lists data on the use of isotretinoin (Roaccutane) for acne treatment of 237 adolescents. Studies were
performed on frequency of occurrence, degree of manifestation of secondary effects and methods of levereging this effects in
practical use. Authors state that correctly prescribed treatments are safe and do not cause serious secondary effects with in case
of long treatmetns.
noted, that modern acne therapy is able not only to pathogenetically influence consequences of the process, but effect genetical
causes of desease, leading to persistant changes and normalization of regulatory segments DNA structure under influence of
isotretinoin. Also this article lists data on the use of isotretinoin (Roaccutane) for acne treatment of 237 adolescents. Studies were
performed on frequency of occurrence, degree of manifestation of secondary effects and methods of levereging this effects in
practical use. Authors state that correctly prescribed treatments are safe and do not cause serious secondary effects with in case
of long treatmetns.
Keywords
References
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Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).