SYSTEM THERAPY OF PSORIASIS IN CHILDREN (PART I)

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Abstract

We include a review of modern methods of systemic therapy of psoriasis in children, indications for which are moderate and severe forms of psoriasis with PASI > 10, skin pathological process that is uncontrollable with topical drugs, skin lesions with functional localization (lesions of genitals, palms and soles, facial skin), erythrodermic psoriasis, pustular psoriasis, psoriatic arthritis. We provide information on the techniques of narrow-band phototherapy (UVB 311 nm) that are used in the treatment of psoriasis in children. We provide data on efficacy, safety, necessary monitoring of clinical and laboratory indicators, peculiarities of vaccination during treatment of children with acitretin, methotrexate, cyclosporine.

About the authors

L. S. Namazova-Baranova

FSAI “SCCH” of the Ministry of Health of the Russian Federation

Author for correspondence.
Email: m_nn2001@mail.ru

Lomonosovsky prospekt, 2, bldg 1, Moscow, 119991, Russia

 

Россия

N. N. Murashkin

FSAI “SCCH” of the Ministry of Health of the Russian Federation; FGBU DPO "Central State Medical Academy"; I.M. Sechenov First Moscow State Medical University

Email: fake@neicon.ru
Lomonosovsky prospekt, 2, bldg 1, Moscow, 119991, Russia; Marshal Timoshenko str., 19, bldg 1A, Moscow, 121359, Russia;  Trubetskaya str., 8, bldg 2, Moscow, 119991, Russia Россия

EH. T. Ambarchyan

FSAI “SCCH” of the Ministry of Health of the Russian Federation

Email: fake@neicon.ru
Lomonosovsky prospekt, 2, bldg 1, Moscow, 119991, Russia; Marshal Timoshenko str., 19, bldg 1A, Moscow, 121359, Russia;  Trubetskaya str., 8, bldg 2, Moscow, 119991, Russia Россия

A. I. Materikin

FSAI “SCCH” of the Ministry of Health of the Russian Federation

Email: fake@neicon.ru
Lomonosovsky prospekt, 2, bldg 1, Moscow, 119991, Russia; Marshal Timoshenko str., 19, bldg 1A, Moscow, 121359, Russia;  Trubetskaya str., 8, bldg 2, Moscow, 119991, Russia Россия

References

  1. Baranov A. A., Nama zova-Baranova L. S., Murashkin N. N., Krug lova L. S., Epishev R. V., Ambarchyan EH. T., Materikin A. I., Federal'nye klinicheskie rekomendacii po okazaniyu medicinskoj pomoshchi detyam s psoriazom 2016; 5—10. [Баранов А. А., Намазова-Баранова Л. С., Мурашкин Н. Н., Круглова Л. С., Епишев Р. В., Амбарчян Э. Т., Материкин А. И., Федеральные клинические рекомендации по оказанию медицинской помощи детям с псориазом 2016; 5—10.]
  2. Huerta C., Rivero E., Rodriguez L. A. Incidence and risk factors for psoriasis in the general population. Arch Dermatol 2007; 143: 1559—65.
  3. Raychaudhuri S. P., Gross J. A comparative study of pediatric onset psoriasis with adult onset psoriasis. Pediatr Dermatol 2000; 17: 174—8.
  4. Murashkin N. N. Ocenka ehffektivnosti supressivnoj terapii tyazhelyh form psoriaza u detej. Pediatr farmakol 2007: 5 (4): 48—52. [Мурашкин Н. Н. Оценка эффективности супрессивной терапии тяжелых форм псориаза у детей. Педиатр фармакол 2007: 5 (4): 48—52.]
  5. Potekaev N. N., Kruglova L. S. Psoriaticheskaya bolezn'. M: MDF 2014; 298. [Потекаев Н. Н., Круглова Л. С. Псориатическая болезнь. М: МДФ 2014; 298.]
  6. Corrales I. L., Ramnarine S., Lansang P. Treatment of Childhood Psoriasis with Phototherapy and Photochemotherapy Clinical Medicine Insights. Pediatrics 2013; 7—33.
  7. Napolitano M., Megna M., Balato A., Ayala F., Lembo S., Villani A., Balato N. Systemic Treatment of Pediatric Psoriasis: A Review. Dermatol Ther (Heidelb) 2016 Jun; 6 (2): 125—42.
  8. Holme S. A., Anstey A. V. Phototherapy and PUVA photochemotherapy in children. Photodermatol Photoimmunol Photomed 2004; 20: 69—75.
  9. Goktas E., Aydin F., Senturk N. et al. Mechanism of ultraviolet (UV) В and UVA phototherapy. J EADV 2006; 20 (5): 553—557.
  10. Marqueling A., Cordoro K. M. Systemic treatments for severe pediatric psoriasis: a practical approach. Dermatol Clin 2013; 31: 267—88.
  11. Pavlovsky M., Baum S., Shpiro D., Pavlovsky L., Pavlotsky F. Narrow band UVB: is it effective and safe for paediatric psoriasis and atopic dermatitis? J Eur Acad Dermatol Venereol 2011; 25: 727—9.
  12. Pasic A., Ceovic R., Lipozencic J. et al. Phototherapy in pediatric patients. Pediatr Dermatol 2003; 20: 71—7.
  13. Fouzan A. S., Nanda A. UVB phototherapy in childhood psoriasis. Pediatr Dermatol 1995;12:66.
  14. Tay Y. K., Morelli J. G., Weston W. L. Experience with UVB phototherapy in children. Pediatr Dermatol 1996; 13: 406—9.
  15. Jain V. K., Aggarwal K., Jain K., Bansal A. Narrow-band UV-B phototherapy in childhood psoriasis. Int J Dermatol 2007; 46: 320—2.
  16. Zamberk P., Velazquez D., Campos M., Hernanz J. M., Lazaro P. Paediatric psoriasis: narrowband UVB treatment. J Eur Acad Dermatol Venereol 2010; 24: 415—9.
  17. Murashkin N. N., Ponich E. S., Ambarchyan EH. T. Ul'trafioletovaya terapiya u detej: sovremennye rekomendacii po primeneniyu u bol'nyh psoriazom. Fizioterapevt 2015; 6: 24— 33. [Мурашкин Н. Н., Понич Е. С., Амбарчян Э. Т. Ультрафиолетовая терапия у детей: современные рекомендации по применению у больных псориазом. Физиотерапевт 2015; 6: 24—33.]
  18. Lara-Corrales I., Ramnarine S., Lansang P. Treatment of childhood psoriasis with phototherapy and photochemotherapy. Clin Med Insights Pediatr 2013; 7: 25—33.
  19. Pasic A., Ceovic R., Lipozencic J., et al. Phototherapyin pediatric patients. Pediatr Dermatol 2003; 20: 71—7.
  20. Matz H. Phototherapy for psoriasis: what to choose and how to use: facts and controversies. Clin Dermatol 2010; 28: 73—80.
  21. Dogra S., Kaur I. Childhood psoriasis. Indian J Dermatol Venereol Leprol 2010; 76: 357—65.
  22. Kopp T., Karlhofer F., Szepfalusi Z., Schneeberger A., Stingl G., Tanew A. Successful use of acitretin in conjunction with narrowband ultraviolet B phototherapy in a child with severe pustular psoriasis, von Zumbusch type. Br J Dermatol 2004; 151: 912—6.
  23. Osorio F., Magina S. Phototherapy and photopheresis: old and new indications. Expert Rev Dermatol 2011; 6: 23—613.
  24. Cordoro K. M. Systemic and light therapies for the management of childhood psoriasis: part II. Skin Therapy Lett 2008; 13: 1—3.
  25. Murashkin N. N. Psoriasis therapy in children with use of low dose off immunosuppressive drugs and use of narrowband phototherapy (UVB 311μm). 25th EADV Congress Vienna 2016.
  26. Shah K. N. Diagnosis and treatment of pediatric psoriasis: current and future. Am J Clin Dermatol 2013;14:195–213.
  27. Charbit L., Mahé E., Phan A., et al. Systemic treatments in childhood psoriasis: a French multicentre study on 154 children. Br J Dermatol 2015; doi: 10.1111/bjd.14326
  28. Van Geel M. J., Mul K., de Jager M. E. A., van de Kerkhof P. C. M., de Jong E. M. G. J., Seyger M. M. B. Systemic treatments in paediatric psoriasis: a systematic evidence-based ate. J Eur Acad Dermatol Venereol 2015 Mar; 29 (3): 425—37.
  29. Amy S. Paller, Anthony J. Mancini. Huewitz. Clinical pediatric dermatology. Firstedition P. 82.
  30. Brecher A. R., Orlow S. J. Oral retinoid therapy for dermatologic conditions in children and adolescents. J Am Acad Dermatol 2003; 49: 171—82.
  31. Lee C. S., Koo J. A review of acitretin, a systemic retinoid for the treatment of psoriasis. Expert Opin Pharmacother 2005; 6: 1725—34.
  32. Katugampola R. P., Finlay A. Y. Oral retinoid therapy for disorders of keratinization: singlecentre retrospective 25 years’ experience on 23 patients. Br J Dermatol 2006; 154: 267—76.
  33. Halverstam C. P., Zeichner J., Lebwohl M. Lack of significant skeletal changes after long-term, low-dose retinoid therapy: case report and review of the literature. J Cutan Med Surg. 2006; 10: 291—9.
  34. Kopp T., Karlhofer F., Szépfalusi Z., Schneeberger A., Stingl G., Tanew A. Successful use of acitretin in conjunction with narrowband ultraviolet B phototherapy in a child with severe pustular psoriasis, von Zumbuschtype. Br J Dermatol 2004; 151: 912—6.
  35. Cordoro K. M. Systemic and light therapies for the management of childhood psoriasis: part II. Skin Therapy Lett 2008; 13: 1—3.
  36. Alli N., Góngur E., Karakayali G., Lenk N., Artóz F. The use of cyclosporine in a child with generalized pustular psoriasis. Br J Dermatol 1998; 139: 754—5.
  37. Perrett C. M., Ilchyshyn A., Berth-Jones J. Cyclosporin in childhood psoriasis. J Dermatolog Treat 2003; 14: 113—8.
  38. Pereira T. M., Vieira A. P., Fernandes J. C., Sousa-Basto A. J. Cyclosporin A treatment in severe childhood psoriasis. J Eur Acad Dermatol Venereol 2006; 20: 651—6.
  39. Fotiadou C., Lazaridou E., Ioannides D. Management of psoriasis in adolescence. Adolesc Health Med Ther 2014; 5: 25—34.
  40. Mahé E., Bodemer C., Pruszkowski A, TeillacHamel D., de Prost Y. Cyclosporine in childhood psoriasis. Arch Dermatol 2001; 137: 1532.
  41. Stahle M., Atakan N., Boehncke W. H. et al. Juvenile psoriasis and its clinical management: a European expert group consensus. J Dtsch Dermatol Ges 2010; 8: 812—8.
  42. Di Lernia V., Stingeni L., Boccaletti V. et al. Effectiveness and safety of cyclosporine in pediatric plaque psoriasis: a multicentric retrospective analysis. J Dermatolog Treat 2015;10:1–4.
  43. Warren R. B., Chalmers R. J., Griffiths C. E., Menter A. Methotrexate for psoriasis in the era of biological therapy. Clin Exp Dermatol 2008;33:551–4.
  44. Van Geel M. J., Oostveen A. M., Hoppenreijs E. P. et al. Methotrexate in pediatric plaque-type psoriasis: long-term daily clinical practice results from the Child-CAPTURE registry. J Dermatol Treat 2015; 20: 1—7.
  45. M. J. Van Geel, P. C. Van de Kerkhof, A. M. Oostveen, E. M. de Jong, M. M. Seyger. Fumaric acid esters in recalcitrant pediatric psoriasis: A prospective, daily clinical practice case series. J Dermatolog Treat. 2016; 27 (3): 214—20.
  46. Ramanan A. V. Vakcinacii i infekcii u pacientov, poluchayushchih biologicheskuyu terapiyu. EHffektivnaya farmakoterapiya. Pediatriya 2015; 2 (15): 58. [Раманан А. В. Вакцинации и инфекции у пациентов, получающих биологическую терапию. Эффективная фармакотерапия. Педиатрия 2015; 2 (15): 58.]

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Copyright (c) 2017 Namazova-Baranova L.S., Murashkin N.N., Ambarchyan E.T., Materikin A.I.

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