Vol 87, No 1 (2011)

An analysis of quality of maintenance for outpatient individual medical records at dermatovenerological settings.

Modern data of the epidemiological aspects and clinical peculiarities of inflammatory urogenital diseases caused by genital mycoplasmas in children are represented. Contemporary methods of laboratory diagnostics and therapy for inflammatory urogenital diseases caused by genital mycoplasmas are described.

The performed investigation has shown that there is an increase of the content of CD4+ lymphocytes and an increased expression of γ-interferon in the skin of patients with atopic dermatitis comparing to healthy volunteers. Therapy with the use of UFA-1 produced more marked levels of γ-interferon positive cells in the skin (р = 0.004) in patients with clinical recovery compared to subjects with an achieved improvement, as well as a substantial reduction of the Т-helpers level within the effected skin areas (р = 0.009).

To investigate the actual practice of antibacterial therapy of sexually-transmitted bacterial diseases (STD) in adult patients at the various regions of the Russian Federation as well as to evaluate the concordance of the antibacterial therapy with national standards, a multicenter retrospective analytical trial was carried out. Investigational data of 1250 subjects (61% males, 39% females, the mean age of 28.8 ± 9.2) with early types of Lues (n = 341), uncomplicated urogenital gonococcal infection (n = 309), candidiasis (n = 310), mycoplasmosis (n = 137) and ureaplasma infection (n = 153), being treated at prevention and treatment facilities of 10 cities of Russia from January to December 2007 were analysed. 1567 prescriptions for the treatment of the underlying disease were registered, among which 1352 (86.2%) prescriptions regarded antibacterial agents. The therapy of early forms of Lues most frequently included benzathine benzylpenicillin (38.4%), procaine penicillin (28.3%), ceftriaxone (26.9%), and benzylpenicillin (5.5%); therapy of uncomplicated urogenital gonococcal infection included: ceftriaxone (57.5%), spectinomycin (9.3%), doxycycline (7.2%), and azithromycin (5.1%); urogenital chlamydial infections: azithromycin (28.2%), doxycycline (22.2%), clarithromycin (14.9%), josamycin (11.1%), and ofloxacin (7.9%); urogenital mycoplasmal and ureaplasmal infections: doxycycline (32.4 and 31.3%), josamycin (21.4 and 21.3%), azithromycin (15.2 and 11.3%), clarithromycin (14.5 and 11.3%), levofloxacin (4.1 and 6.9%). Frequency of administration of ther drugs was less then 5% for each one. The study has demonstrated a high variability of choice of antibacterial agents by physicians along with an evident tendency to exceeding the total doses during the course therapy. The prescribed therapy was conforming with national recommendations in 71.8% of the subjects, while the total treatment doses were consistent with recommended doses in 24% of patients only, that indicates a necessity to change the established practice of bacterial STD therapy in Russia.

Analysis of the incidence and clinical peculiarities of the bullous epidermolysis in children at Krasnodar Territory circumstances is represented. The authors conclude that there is a growth of the incidence of the various forms of bullous epidermolysis in pediatric patients. They describe the results of analysis concerning the present clinical polymorphism of the disease.

Cryoablation of hemangiomas and viral warts was performed after preliminary injection of the angioprotective Solution Dicynon 12.5%. The agent contributed to hemostasis and thrombosis in the area of cryoablation that intensified the cryoablation. A beneficial postoperative course, the reduction of the frequency of hyperkeratosis relapses was noted along with an enhanced control of cryoablation. The therapy approach may be advised for the use in the dermatovenerology and cosmetology practice as well as a treatment modality at pediatric surgical departments.

Data of the literature concerning peculiarities of the course of ichthyosis hystrix and its pathomorphological picture along the description of a clinical case of the rare form of the disease based on authors' own practice are represented.

The article contains the literature data concerning the efficacy and safety of topic antibiotics for treatment of acne. The results of studies investigating the efficacy of clindamycin external formulations in patients with acne are shown.

The results of therapy for palmar & plantar psoriasis with topic glucocorticosteroids and a moisturizing agent.

The article represents the data of the literature concerning peculiarities of the clinical manifestation of androgenic alopecia in females as well as the results of authors' investigations of morphometrical hair parameters obtained both by trichoscopy and phototrichography in 87 patients with androgenic alopecia and in 30 healthy female volunteers. The obtained data indicate a reduction of hair density in females with androgenic alopecia (mainly in the androgen-dependant area), a decrease of average hair diameter as well as an increase (more than twice) of the percentage of lost hairs compared to the control group.